Select publications

Dey, A.*, Talla, M.*, Schneider, E.*, Pham, A., Alsumaili…et al…, Sadow, P., Maus, M.V., Slabicki, M., Villani, A.-C.*, and Jan, M.* Cell atlas-resolved discovery and targeting of novel CAR antigens in anaplastic thyroid carcinoma. In preparation.

Sarkar, D., Lin, W., Knudsen, N.H., Evans, J., Kim, J.Y., Coscia, S.M., Lane, I.C., Cheng, A., Radde, N., Talla, M., Kienka, T., Schneider, E., Kembuan, G., Maus, M.V., Manguso, R.T., A Lenalidomide-Inducible Suicide Switch for Gene- and Cell-Based Therapy. In preparation.

Kembuan, G. J.*, Kim, J. Y.*, Maus, M. V., & Jan, M. (2024). Targeting solid tumor antigens with chimeric receptors: cancer biology meets synthetic immunology. Trends in Cancer, https://doi.org/10.1016/j.trecan.2024.01.003.

Kann, M. C., Schneider, E. M., Almazan, A. J., Lane, I. C., Bouffard, A. A., Supper, V. M., Takei, H. N., Tepper, A., Leick, M. B., Larson, R. C., Ebert, B. L., Maus, M. V., & Jan, M. (2023). Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7. Leukemia, 1-11.

Lane, I. C., Kembuan, G., Carreiro, J., Kann, M. C., Lin, W., Bouffard, A. A., Kreuzer, J., Morris, R., Schneider E. M., Kim, J. Y., Zou, C., Salas-Benito, D., Gasser, J. A., Leick, M. B., Slabicki, M., Haas, W., Maus, M. V., & Jan, M. (2023). Genetic retargeting of E3 ligases to enhance CAR T cell therapy. Cell Chemical Biology, Nov 14:S2451-9456(23)00386-0.

Lane, I. C. & Jan, M. (2022). SEAKER cells coordinate cellular immunotherapy with localized chemotherapy. Trends in Pharmacological Sciences.

Jan, M.*, Sperling, A. S.*, & Ebert, B. L. (2021). Cancer therapies based on targeted protein degradation—lessons learned with lenalidomide. Nature Reviews Clinical Oncology, 1-17. *equal contribution.

Jan, M., Scarfò, I., Larson, R. C., Walker, A., Schmidts, A., Guirguis, A. A., ... Maus, M. V., & Ebert, B. L. (2021). Reversible ON-and OFF-switch chimeric antigen receptors controlled by lenalidomide. Science translational medicine, 13(575).

Jan, M., Leventhal, M. J., Morgan, E. A., Wengrod, J. C., Nag, A., Drinan, S. D., ... & Ebert, B. L. (2019). Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation. Blood advances, 3(14), 2199-2204.

Jan, M.*, Snyder, T. M.*, Corces-Zimmerman, M. R.*, Vyas, P., Weissman, I. L., Quake, S. R., & Majeti, R. (2012). Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Science translational medicine, 4(149), 149ra118-149ra118. *equal contribution.

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